Selectfluor Mediated Direct C–H Fluorination of 3-Heteroaryl-Oxindoles,The Journal of Organic Chemistry

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Selectfluor Mediated Direct C–H Fluorination of 3-Heteroaryl-Oxindoles
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2023-12-15 , DOI: 10.1021/acs.joc.3c02063
Hui Qin _{1,

2} , Guo-Liang Wei ₁ , Xiao-Wei Zheng _{1,

2} , Yi-Wen Zhang _{1,

2} , Ping Huang _{1,

2}

Affiliation

An efficient transition-metal-free fluorination synthesis of N-H-free 3-heteroaryl-oxindoles with Selectfluor was depicted. Under mild reaction conditions, a series of 3-heteroaryl-fluorooxindoles were produced in yield of 62–88% using Selectfluor as a fluorine source.

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