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Molecular design of microalgae as sustainable cell factories
Trends in Biotechnology ( IF 14.3 ) Pub Date : 2023-12-12 , DOI: 10.1016/j.tibtech.2023.11.010 Alexander Einhaus 1 , Thomas Baier 1 , Olaf Kruse 1
Trends in Biotechnology ( IF 14.3 ) Pub Date : 2023-12-12 , DOI: 10.1016/j.tibtech.2023.11.010 Alexander Einhaus 1 , Thomas Baier 1 , Olaf Kruse 1
Affiliation
Microalgae are regarded as sustainable and potent chassis for biotechnology. Their capacity for efficient photosynthesis fuels dynamic growth independent from organic carbon sources and converts atmospheric CO directly into various valuable hydrocarbon-based metabolites. However, approaches to gene expression and metabolic regulation have been inferior to those in more established heterotrophs (e.g., prokaryotes or yeast) since the genetic tools and insights in expression regulation have been distinctly less advanced. In recent years, however, these tools and their efficiency have dramatically improved. Various examples have demonstrated new trends in microalgal biotechnology and the potential of microalgae for the transition towards a sustainable bioeconomy.
中文翻译:
微藻作为可持续细胞工厂的分子设计
微藻被认为是生物技术可持续且有效的基础。它们高效光合作用的能力可以独立于有机碳源推动动态生长,并将大气中的二氧化碳直接转化为各种有价值的碳氢化合物代谢物。然而,基因表达和代谢调节的方法不如更成熟的异养生物(例如原核生物或酵母)中的方法,因为表达调节的遗传工具和见解明显不够先进。然而,近年来,这些工具及其效率有了显着提高。各种例子证明了微藻生物技术的新趋势以及微藻向可持续生物经济过渡的潜力。
更新日期:2023-12-12
中文翻译:
![](https://scdn.x-mol.com/jcss/images/paperTranslation.png)
微藻作为可持续细胞工厂的分子设计
微藻被认为是生物技术可持续且有效的基础。它们高效光合作用的能力可以独立于有机碳源推动动态生长,并将大气中的二氧化碳直接转化为各种有价值的碳氢化合物代谢物。然而,基因表达和代谢调节的方法不如更成熟的异养生物(例如原核生物或酵母)中的方法,因为表达调节的遗传工具和见解明显不够先进。然而,近年来,这些工具及其效率有了显着提高。各种例子证明了微藻生物技术的新趋势以及微藻向可持续生物经济过渡的潜力。