A novel rhodium catalytic system with Naphos as ligand was developed for an efficient hydroaminomethylation of 1,1-diphenylethene under relatively mild conditions. This will allow for an atom-economic and environmentally benign synthesis of fenpiprane and related pharmaceuticals.

中文翻译：

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铑催化的氢氨基甲基化级联合成苯丙戊环及相关药物

开发了一种以Naphos为配体的新型铑催化体系，用于在相对温和的条件下有效地进行1,1-二苯乙烯的氢氨基甲基化反应。这将允许芬吡丙烷和相关药物的原子经济和环境友好的合成。