An efficient catalytic process with high productivity (85 % overall yield) is achieved by protecting the reactive formyl group of 5-hydroxymethylfurfural (HMF) with methanol (HMF-acetal) for the stepwise synthesis of dimethyl furan-2,5-dicarboxylate (MFDC) under mild reaction conditions. The developed process reduces the amount of base significantly and expand the scope of acetal functionality towards biobased polyester production.

中文翻译：

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以甲醇为缩醛化剂以5-羟甲基糠醛高产率合成2,5-呋喃二甲酸二甲酯的保护策略

通过用甲醇（HMF-乙缩醛）保护 5-羟甲基糠醛（HMF）的反应性甲酰基，逐步合成 2,5-二甲酸二甲酯呋喃（MFDC），实现了高产率（85% 总收率）的高效催化过程。 ）在温和的反应条件下。所开发的工艺显着减少了碱的用量，并扩大了缩醛官能团的范围，用于生物基聚酯的生产。