Transcatheter closure of VSD remains a complex procedure in infants with technical challenges and carries the risk of significant complications, due to its complex anatomical morphology and closed proximity to the atrioventricular valves and the conduction system. In this article, we presented transcatheter VSD closure in infants under 10 kg using the Lifetech Konar-MF device via only venous route without TEE guidance and arterial access. Between January 2021 and May 2023, a total of 34 patients weighing less than 10 kg who underwent transcatheter VSD closure antegradely with Lifetech™ Konar-Multifunctional (MF) occluder were included in the study. The mean age of the patients was 8.1 (3.5–35) months. Average weight was 6.5 kg (range 4.5–10 kg). VSD was perimembranous in 27 patients (79.4%). Successful device placement was achieved in all 34 patients. However, device embolization occurred in three patients. One of the patients was successfully implanted with a one size larger device, the surgical closure was performed other two cases. TR occurred in seven patients (20.6%) after releasing devices. None of the patients developed complete heart block. Right bundle branch block developed in two patients. Residual shunt was observed in 9 patients (six small, two moderate, and one large). During follow-up, residual shunt disappeared in six of these patients and only mild residual shunt remained in the other four patients which have not required any further intervention. Transcatheter closure of VSD with Lifetech Konar-MF device is safe and effective in infants less than 10 kg via only venous access with a high success rate and low complication rate. In these patients, transcatheter VSD closure can be performed by excluding the risk of complications that may occur due to AV loop formation, arterial intervention, endotracheal intubation and TEE use.

对于婴儿来说，经导管封堵 VSD 仍然是一个复杂的手术，具有技术挑战，并且由于其复杂的解剖形态以及靠近房室瓣和传导系统而存在严重并发症的风险。在本文中，我们介绍了使用 Lifetech Konar-MF 装置对 10 公斤以下婴儿进行经导管 VSD 封堵术，仅通过静脉途径，无需 TEE 引导和动脉通路。 2021 年 1 月至 2023 年 5 月期间，共有 34 名体重小于 10 公斤的患者纳入研究，这些患者使用先健™ Konar 多功能 (MF) 封堵器顺行经导管 VSD 封堵术。患者的平均年龄为 8.1（3.5-35）个月。平均体重为 6.5 公斤（范围 4.5-10 公斤）。 27 名患者 (79.4%) 发生膜周室间隔缺损 (VSD)。所有 34 名患者均成功植入装置。然而，三名患者发生了装置栓塞。其中一名患者成功植入了大一号的装置，另外两名患者则进行了手术闭合。释放装置后，7 名患者（20.6%）发生 TR。没有患者出现完全性心脏传导阻滞。两名患者出现右束支传导阻滞。在 9 名患者中观察到残余分流（6 名小型患者、2 名中型患者和 1 名大型患者）。在随访期间，其中 6 名患者的残余分流消失，另外 4 名患者仅保留轻度残余分流，无需任何进一步干预。使用先健科技 Konar-MF 装置经导管封堵 VSD 对于体重小于 10 公斤的婴儿仅通过静脉通路进行是安全有效的，且成功率高且并发症发生率低。 在这些患者中，可以通过排除因 AV 环形成、动脉介入、气管插管和 TEE 使用而可能发生的并发症的风险来进行经导管 VSD 封堵。