<br>含氟农药的最新进展,Pest Management Science

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含氟农药的最新进展
Pest Management Science ( IF 3.8 ) Pub Date : 2023-12-10 , DOI: 10.1002/ps.7921
Peter Jeschke ₁

Affiliation

为了确保持续的可持续性，现代农化行业面临着巨大的挑战。这些问题源于高质量食品的供应、用水量的增加、环境影响以及世界人口的增长。由于消费者认知、不断变化的种植者需求和不断变化的监管要求，以前农用化学品的损失量高于引入作物保护市场的活性成分的数量。因此，开发新型农用化学品对于提高功效和环境特征至关重要。在这种情况下，将氟原子和含氟基序引入分子中是影响其物理化学性质的重要方法。这些包括例如芳基或杂环芳基部分的小二氟和三氟甲基或三氟甲氧基，还包括片段如2,2,2-三氟乙氧基羰基、三氟甲磺酰基、三氟乙酰基，以及迄今为止不常见的其余基团如七氟-异-丙基。本综述概述了过去 7 年推出的含氟农药的最新进展，并介绍了当前候选含氟农药的选择。 © 2023 作者。 《害虫管理科学》由 John Wiley & Sons Ltd 代表化学工业协会出版。

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Recent developments in fluorine-containing pesticides

To ensure ongoing sustainability, the modern agrochemical industry is faced with enormous challenges. These arise from provision of high-quality food to increasing water use and environmental impact as well as a growing world population. The loss of previous agrochemicals due to consumer perception, changing grower needs and ever-changing regulatory requirements is higher than the number of active ingredients that are being introduced into the crop protection market. Therefore, the development of novel agrochemicals is essential to provide improved efficacy and environmental profiles. In this context, the introduction of fluorine atoms and fluorine-containing motifs into a molecule is an important method to influence its physicochemical properties. These include, for example, small difluoro- and trifluoromethyl, or trifluoromethoxy groups at aryl or heterocyclic aryl moieties but also fragments like 2,2,2-trifluoroethoxycarbonyl, trifluoromethylsulfonyl, trifluoroacetyl, as well as the so far unusal rest like heptafluoro-iso-propyl. This review gives an overview of recent developments of fluorine-containing pesticides launched over the past 7 years and describes a selection of current fluorine-containing development candidates. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

更新日期：2023-12-10

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