The human oral cavity is normally colonized by microorganisms including bacteria, fungi, archaea, viruses and protozoa. The aim of this study was to determine the frequency of Candida spp., in de oral cavity in a group of medical students from the north of Mexico. Oral sample were obtained from 240 healthy students. The specimens were analyzed by traditional microbiology cultures and DNA sequencing. Candida spp., grew in Sabouraud dextrose agar from 57 samples and subsequently were isolated and phenotyped. The definitive identification to the species level was done by sequence analysis. The yeasts were identified as follow: 28 Clavispora lusitaniae, 20 Candida albicans, 5 Pichia kudriavzevii and 4 Candida parapsilosis. Our findings revealed that 23.75% of the healthy population has a potential pathogen in their mouth. Surprisingly, C. albicans is not the predominant yeast; instead other non-Candida species are the colonizers of the oral cavity as normal microbiota. C. lusitaniae is considered an emerging opportunistic pathogen in immunosuppressive patients. This paper pretends to highlight the presence of this yeast in the oral cavity in immunocompetent young adults.

人类口腔通常栖息着微生物，包括细菌、真菌、古细菌、病毒和原生动物。本研究的目的是确定来自墨西哥北部的一组医科学生口腔中念珠菌属的频率。口腔样本取自 240 名健康学生。通过传统微生物培养和 DNA 测序对样本进行分析。念珠菌属 ( Candida spp.) 在 57 个样品的沙氏葡萄糖琼脂中生长，随后进行分离和表型分析。通过序列分析完成物种水平的明确鉴定。经鉴定酵母菌如下： Clavispora lusitaniae 28 株、白色念珠菌20 株、库德里阿泽维毕赤酵母5 株、近平滑念珠菌4 株。我们的研究结果显示，23.75% 的健康人群口腔中存在潜在病原体。令人惊讶的是，白色念珠菌并不是主要的酵母菌。相反，其他非念珠菌物种作为正常微生物群在口腔中定殖。卢西塔尼梭菌被认为是免疫抑制患者中新出现的机会性病原体。这篇论文试图强调免疫功能健全的年轻人口腔中存在这种酵母菌。