The class of insecticides known as neonicotinoid insecticides has gained extensive application worldwide. Two characteristics of neonicotinoid pesticides are excellent insecticidal activity and a wide insecticidal spectrum for problematic insects. Neonicotinoid pesticides can also successfully manage pest insects that have developed resistance to other insecticide classes. Due to its powerful insecticidal properties and rapid plant absorption and translocation, dinotefuran, the most recent generation of neonicotinoid insecticides, has been widely used against biting and sucking insects. Dinotefuran has a wide range of potential applications and is often used globally. However, there is growing evidence that they negatively impact the biodiversity of organisms in agricultural settings as well as non-target organisms. The objective of this review is to present an updated summary of current understanding regarding the non-target effects of dinotefuran; we also enumerated nano- and bio-based mitigation and management strategies to reduce the impact of dinotefuran on non-target organisms and to pinpoint knowledge gaps. Finally, future study directions are suggested based on the limitations of the existing studies, with the goal of providing a scientific basis for risk assessment and the prudent use of these insecticides.

被称为新烟碱类杀虫剂的杀虫剂类别已在全世界得到广泛应用。新烟碱类农药的两个特点是具有优异的杀虫活性和对问题昆虫的杀虫谱广。新烟碱类杀虫剂还可以成功地防治对其他杀虫剂类别产生抗药性的害虫。呋虫胺是最新一代的新烟碱类杀虫剂，由于其强大的杀虫特性和快速的植物吸收和转运，已被广泛用于防治刺吸式昆虫。呋虫胺具有广泛的潜在应用，并且经常在全球范围内使用。然而，越来越多的证据表明它们对农业环境中的生物以及非目标生物的生物多样性产生负面影响。本次审查的目的是对呋虫胺非目标效应的当前认识进行更新总结；我们还列举了基于纳米和生物的缓解和管理战略，以减少呋虫胺对非目标生物体的影响并查明知识差距。最后，根据现有研究的局限性，提出了未来的研究方向，旨在为风险评估和审慎使用这些杀虫剂提供科学依据。