Barium sulfate and iohexol are commonly used as contrast agents for videofluoroscopic swallowing study (VFSS). This study compared their usefulness as contrast agents in visualizing components of swallowing predictable of subsequent pneumonia and unintentional weight loss after VFSS. This was a randomized, controlled, crossover trial. The two contrast agents were alternately used in the same participants, and the order in which the contrast agent was tested first was randomly assigned. After VFSS, we followed the participants for 3 months and the association between VFSS findings of each contrast agent and the subsequent pneumonia and unintentional weight loss were analyzed. A total of 30 participants were included in the analysis. We recorded 11 cases of subsequent pneumonia and 13 of unintentional weight loss. Regarding the risk of subsequent pneumonia after VFSS, only the oral transit time and number of swallows tested with barium sulfate indicated significant differences between participants with and without subsequent pneumonia. For unintentional weight loss, oral transit time and pharyngeal wall coating after swallowing tested with barium sulfate, as well as oral transit time, nasal penetration, residue in the valleculae, PAS scores, and number of swallows when testing with iohexol demonstrated significant differences between those with and without unintentional weight loss.

硫酸钡和碘海醇通常用作电视荧光吞咽检查（VFSS）的造影剂。这项研究比较了它们作为造影剂在可视化吞咽成分（可预测随后的肺炎）和 VFSS 后意外体重减轻方面的用途。这是一项随机、对照、交叉试验。两种造影剂在同一参与者中交替使用，并且首先测试造影剂的顺序是随机分配的。 VFSS 后，我们对参与者进行了 3 个月的跟踪，并分析了每种造影剂的 VFSS 结果与随后的肺炎和意外体重减轻之间的关联。共有 30 名参与者参与分析。我们记录了 11 例随后出现的肺炎病例和 13 例体重意外减轻的病例。关于 VFSS 后继发肺炎的风险，只有硫酸钡测试的口腔通过时间和吞咽次数表明有和没有继发肺炎的参与者之间存在显着差异。对于无意识体重减轻，用硫酸钡测试吞咽后的口腔通过时间和咽壁涂层，以及用碘海醇测试时的口腔通过时间、鼻渗透、谷残留、PAS评分和吞咽次数显示出显着差异有或没有无意的体重减轻。