As an important carbon fixation carrier, the plant is extremely susceptible to a variety of environmental influences during its growth and development, which not only manifest themselves morphologically but also lead to disruptions in the metabolic processes within the plant body. In order to maintain its normal growth and development needs, the plant body has evolved a complete set of defence mechanisms. As an important post-translational modification process, ubiquitination is widely involved in plant growth and development as well as abiotic stress processes. This paper briefly introduces the members of ubiquitination and the number of members in each species in the context of domestic and international studies on the ubiquitination system, and focuses on the molecular functions and regulatory mechanisms of the ubiquitination process in the process of plant response to abiotic stress pathways, such as drought stress, salt stress, etc., providing a direction for future research on ubiquitination-mediated abiotic stress and a reference for research on the use of germplasm resources for resistant plants. This study will provide a reference for future research on ubiquitination-mediated abiotic stresses and the use of germplasm resources of resistant crops.