INTRODUCTION There is a paucity of data on the real-world effectiveness of therapies in patients with Crohn's disease of the pouch. METHODS This was a prospective multicenter study evaluating the primary outcome of remission at 12 months of therapy for Crohn's disease of the pouch. RESULTS One hundred thirty-four patients were enrolled. Among the 77 patients with symptoms at baseline, 35 (46.7%) achieved remission at 12 months. Of them, 12 (34.3%) changed therapy. There was no significant association between therapy patterns and remission status. DISCUSSION Approximately 50% with symptoms at enrollment achieved clinical remission at 12 months, most of whom did so without a change in therapy.

中文翻译：

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治疗的改变与袋性克罗恩病患者的缓解率增加无关。


引言 关于克罗恩氏袋病患者治疗的实际有效性的数据很少。方法 这是一项前瞻性多中心研究，评估了育儿袋克罗恩病治疗 12 个月后缓解的主要结果。结果 134 名患者入组。在 77 名基线时出现症状的患者中，35 名 (46.7%) 在 12 个月时获得缓解。其中 12 人（34.3%）改变了治疗方法。治疗模式和缓解状态之间没有显着关联。讨论 大约 50% 入组时出现症状的患者在 12 个月时获得临床缓解，其中大多数人在没有改变治疗的情况下实现了临床缓解。