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Designing RNA switches for synthetic biology using inverse-RNA-folding
Trends in Biotechnology ( IF 14.3 ) Pub Date : 2023-12-01 , DOI: 10.1016/j.tibtech.2023.11.005
Sumit Mukherjee , Danny Barash

RNA switches respond to specific ligands to control gene expression. They are widely used in synthetic biology applications and hold potential for future RNA-based therapeutic breakthroughs. However, the crux is their precise design. Here, we will discuss how inverse-RNA-folding could be utilized for the accurate design of RNA switches.

中文翻译:

使用反向 RNA 折叠设计用于合成生物学的 RNA 开关

RNA 开关响应特定配体来控制基因表达。它们广泛用于合成生物学应用,并具有未来基于 RNA 的治疗突破的潜力。然而,关键在于它们的精确设计。在这里,我们将讨论如何利用反向 RNA 折叠来精确设计 RNA 开关。
更新日期:2023-12-01
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