PURPOSE As high rates of vitamin D deficiency have been demonstrated in orthopaedic patient cohorts, this study aims to characterize the association between a diagnosis of hypovitaminosis D and primary rotator cuff tear (RCT), primary rotator cuff repair (RCR), and postoperative complications in different sex and age cohorts. METHODS In this retrospective cohort study using PearlDiver, a nationwide administrative claims database, records for all patients aged 30 to 89 who received a diagnosis of hypovitaminosis D between January 1st, 2011 to October 31st, 2018 were queried. Rates of primary RCT, primary RCR, and postoperative complications including subsequent surgery were calculated within sex- and age-specific cohorts and compared to matched control cohorts using multivariable logistic regression. RESULTS Among the 336,320 patients included in the hypovitaminosis D cohort, these patients were significantly more likely to experience a RCT (OR = 2.70, 95% CI, 2.55 - 2.85) as well as a full-thickness RCT (OR 2.36, 95% CI, 2.17 - 2.56) specifically within 2 years of their diagnosis. Females with hypovitaminosis D were more likely to undergo surgery to address their full-thickness tears (OR = 1.37, 95% CI, 1.09 - 1.74). There was no difference in the rates of revision RCR or irrigation and debridement. However, female with hypovitaminosis D were significantly more likely to undergo manipulation under anesthesia (OR = 1.16, 95% CI, 1.03 - 1.31). CONCLUSIONS Patients diagnosed with hypovitaminosis D were significantly more likely to suffer a primary RCT and to undergo manipulation under anesthesia within a year of their rotator cuff repair. While many risk factors for RCT are unmodifiable, vitamin D deficiency is a readily modifiable risk factor with several treatment regimens demonstrating positive effects on musculoskeletal health.

中文翻译：

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维生素 D 缺乏症的诊断与肩袖撕裂之间存在显着关联，与年龄和性别无关：一项回顾性数据库研究。

目的 由于骨科患者群体中维生素 D 缺乏率较高，本研究旨在探讨维生素 D 缺乏症诊断与原发性肩袖撕裂 (RCT)、原发性肩袖修复 (RCR) 和术后并发症之间的关系。不同性别和年龄的群体。方法在这项回顾性队列研究中，使用全国行政索赔数据库PearlDiver，查询了2011年1月1日至2018年10月31日期间所有被诊断为维生素D缺乏症的30岁至89岁患者的记录。在特定性别和年龄的队列中计算主要 RCT、主要 RCR 和术后并发症（包括后续手术）的发生率，并使用多变量逻辑回归与匹配的对照队列进行比较。结果 在维生素 D 缺乏症队列中纳入的 336,320 名患者中，这些患者更有可能接受 RCT（OR = 2.70，95% CI，2.55 - 2.85）以及全层 RCT（OR 2.36，95% CI） ，2.17 - 2.56）特别是在诊断后 2 年内。患有维生素 D 缺乏症的女性更有可能接受手术来解决全层撕裂问题（OR = 1.37，95% CI，1.09 - 1.74）。RCR 翻修率或冲洗和清创率没有差异。然而，维生素 D 缺乏症的女性更有可能在麻醉下接受操作（OR = 1.16，95% CI，1.03 - 1.31）。结论 诊断为维生素 D 缺乏症的患者在肩袖修复后一年内接受初次随机对照试验并接受麻醉操作的可能性明显更大。虽然 RCT 的许多危险因素是不可改变的，但维生素 D 缺乏是一个容易改变的危险因素，多种治疗方案显示出对肌肉骨骼健康的积极影响。