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[Advances in pharmacological effects of jujuboside B].
China Journal of Chinese Materia Medica Pub Date : 2023-08-01 , DOI: 10.19540/j.cnki.cjcmm.20230320.701
Xiao-Na Dong 1 , Meng-Ting Li 1 , Hui-Yang Gu 2 , Ye Zhu 3 , Xiang Gu 3
Affiliation  

Ziziphi Spinosae Semen(ZSS) is an edible TCM derived from the dried ripe seeds of Ziziphus jujube Mill. var. spinosa(Bunge)Hu ex H. F. Chou(Rhamnaceae), which has the effects of nourishing the heart, tonifying the liver, calming the heart, tranquilizing the mind, arresting sweating, and promoting fluid production, and is widely used in the treatment and health care of diseases related to cardiovascular, nervous, and immune systems. Jujuboside B(JuB), one of the main active ingredients of ZSS, possesses various pharmacological effects with application values. This paper reviewed the chemical structure and pharmacological effects of JuB. JuB has sedative, hypnotic, antitumor, anti-platelet, anti-inflammatory, and other biological activities, which shows the potential thera-peutic effects on insomnia, tumors, coronary artery disease, airway inflammation, and liver injury. However, there are some limitations to the results of current studies. More comprehensive studies, including basic research and clinical trials, need to be carried out to provide more reliable evidence.

中文翻译:

酸枣仁苷B的药理作用研究进展[J].

枣子(Ziziphi Spinosae Semen,ZSS)是一种中药材,来源于枣树的干燥成熟种子。变种 spinosa(Bunge)Hu ex HF Chou(Rhamnaceae),具有养心、补肝、宁心、安神、止汗、生津的功效,广泛用于治疗和保健。护理与心血管、神经和免疫系统相关的疾病。Jujuboside B(JuB)是ZSS的主要活性成分之一,具有多种药理作用,具有应用价值。本文对JuB的化学结构和药理作用进行了综述。JuB具有镇静、催眠、抗肿瘤、抗血小板、抗炎等生物活性,对失眠、肿瘤、冠心病、气道炎症、肝损伤等具有潜在的治疗作用。然而,目前的研究结果存在一些局限性。需要进行更全面的研究,包括基础研究和临床试验,以提供更可靠的证据。
更新日期:2023-08-01
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