Bisphenol A (BPA) functions as a detrimental substance that disrupts the endocrine system in animals while also impeding the growth and development of plants. In our previous study, we demonstrated that BPA hinders the growth of roots in Arabidopsis by diminishing cell division and elongation, which is ascribed to the increased accumulation and redistribution of auxin. Here, we examined the mediation of ROS and ethylene in BPA-induced auxin accumulation and root growth inhibition. BPA enhanced ROS levels, and ROS increased auxin contents but reduced cell division activity and the expression of EXPA8 involved in root elongation. ROS scavenger treatment reversed BPA-triggered root growth retardation, auxin accumulation, and cell division inhibition. In addition, BPA induced ethylene, and ethylene synthesis inhibitor treatment reversed BPA-triggered root growth retardation and auxin accumulation. Taken together, ROS and ethylene are involved in BPA-inhibited cell elongation and cell division by mediating auxin accumulation and redistribution.

双酚 A (BPA) 是一种有害物质，会扰乱动物的内分泌系统，同时也会阻碍植物的生长和发育。在我们之前的研究中，我们证明 BPA 通过减少细胞分裂和伸长来阻碍拟南芥根的生长，这归因于生长素积累和重新分配的增加。在这里，我们研究了 ROS 和乙烯在 BPA 诱导的生长素积累和根生长抑制中的介导作用。 BPA 增强 ROS 水平，ROS 增加生长素含量，但降低细胞分裂活性和参与根伸长的EXPA8表达。 ROS 清除剂处理逆转了 BPA 引发的根部生长迟缓、生长素积累和细胞分裂抑制。此外，BPA 诱导乙烯，乙烯合成抑制剂处理逆转了 BPA 引发的根部生长迟缓和生长素积累。总而言之，ROS 和乙烯通过介导生长素积累和再分配参与 BPA 抑制的细胞伸长和细胞分裂。