Actinorhizal symbiosis naturally harbours beneficial categories of diverse plant growth promoting microorganisms (PGPMs), including the Frankia species. The beneficial microorganisms can be used as efficient, non-chemical and sustainable alternatives for adopting effective soil restoration programmes and revegetation schedules in chemical and industrial-contaminated sites, including treating degraded lands contaminated with toxic chemicals and pesticides. It has been proposed that the interactions between the microbial gene pool are of immense agricultural significance that would facilitate an improvement in the health, hygiene and nutrient acquisition pathway of native soil. The present review is focused on exploiting the hitherto-unexplored Frankia-actinorhizal symbiosis with due interest for their application in soil restoration programmes, including the reclamation of degraded lands. This opens up new insights for the development of sustainability in forestry and plantation research. Additionally, it would promise an improvement in plant growth and vigour, hygiene, and other parameters related to crop yield, such as plant biomass, root/shoot ratio, crop yield, and so on. Novel and putative microorganisms isolated from the actinorhizal may be used for bio-transformation of allelochemicals and toxic heavy metals into compounds with modified biological properties, opening up novel avenues for mediating microbial degradation of putative allelochemicals that would otherwise accumulate at phytotoxic levels in soil. Endophyte-host specificities, the phylogeny of Frankia, and the conservation of unique endemic plant genetic resources like actinorhizal plants, are of paramount significance in the advancement of genomics, metabolomics and phenomics.

放线根共生自然地蕴藏着有益的多种植物生长促进微生物（PGPM），包括Frankia物种。有益微生物可用作高效、非化学和可持续的替代品，在化学和工业污染场地采用有效的土壤恢复计划和植被恢复计划，包括处理被有毒化学品和农药污染的退化土地。有人提出，微生物基因库之间的相互作用具有巨大的农业意义，将有助于改善原生土壤的健康、卫生和养分获取途径。本综述的重点是利用迄今为止尚未探索的Frankia与放线菌共生体，并对其在土壤恢复计划（包括退化土地的开垦）中的应用产生应有的兴趣。这为林业和种植园研究的可持续性发展开辟了新的见解。此外，它还有望改善植物生长和活力、卫生状况以及与作物产量相关的其他参数，例如植物生物量、根/冠比、作物产量等。从放线菌中分离出来的新型和推定微生物可用于将化感物质和有毒重金属生物转化为具有改良生物特性的化合物，从而为介导推定化感物质的微生物降解开辟新途径，否则这些化感物质会在土壤中以植物毒性水平积累。内生菌宿主特异性、Frankia的系统发育以及独特的地方性植物遗传资源（如放线菌植物）的保护，对于基因组学、代谢组学和表型组学的进步具有至关重要的意义。