The selective NOX4 inhibitor GLX7013159 decreases blood glucose concentrations and human beta-cell apoptotic rates in diabetic NMRI nu/nu mice transplanted with human islets,Free Radical Research

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The selective NOX4 inhibitor GLX7013159 decreases blood glucose concentrations and human beta-cell apoptotic rates in diabetic NMRI nu/nu mice transplanted with human islets
Free Radical Research ( IF 3.6 ) Pub Date : 2023-12-26 , DOI: 10.1080/10715762.2023.2284637
Andris Elksnis ₁ , Nils Welsh ₁ , Per Wikström ₂ , Joey Lau ₁ , Per-Ola Carlsson _{1,

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Affiliation

NADPH oxidase 4 (NOX4) inhibition has been reported to mitigate diabetes-induced beta-cell dysfunction and improve survival in vitro, as well as counteract high-fat diet-induced glucose intolerance...

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