Treatment of Spinal Aneurysmal Bone Cyst with Percutaneous Injection of Hydroxyapatite Osteoconductive Cement,CardioVascular and Interventional Radiology

当前位置： X-MOL 学术 › Cardiovasc. Interv. Radiol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Treatment of Spinal Aneurysmal Bone Cyst with Percutaneous Injection of Hydroxyapatite Osteoconductive Cement
CardioVascular and Interventional Radiology ( IF 2.8 ) Pub Date : 2023-11-17 , DOI: 10.1007/s00270-023-03606-8
Eduardo Gragnano ₁ , Valentina Opancina _{2,

3} , Gianluca Muto ₄ , Flavio Giordano ₂ , Gianluigi Guarnieri ₂ , Joshua Hirsch ₅ , Luigi Della Gata ₂ , Enrico Piovan ₆ , Mario Muto ₂

Affiliation

Purpose

The aim of this study was to evaluate treatment efficacy of percutaneous injection of hydroxyapatite-osteoconductive-cement in patients with spinal aneurysmal bone cysts.

Materials and Methods

The study was designed as a retrospective observational clinical study. We included patients who were diagnosed with of spinal aneurysmal bone cyst, at our institution between 2013 and 2020, and treated with percutaneous injection of osteoconductive cement: “Cerament”^® (BONESUPPORT AB, Lund, Sweden). Typical clinical and radiological features of the ABCs treatment and follow-up were investigated.

Results

Our study included nine patients, two children and seven adults. Three different types of approaches were applied: (single pedicle approach in 3 patients; double pedicle approach in 2 patients; while in the remaining cases, a multiple access approach was used. VAS score decreased from 8.5 ± 0.5 before treatment to 4.1 ± 0.9 at 6-months-follow up. All of the patients reacted well to treatment, with none neurological complications, complete loss of pain and achieved osteosclerosis as radiological marker of treatment success.

Conclusion

Treatment of symptomatic spinal ABC’s with hydroxyapatite cement is effective to achieve complete pain reduction and sclerosis.

Graphical Abstract

中文翻译：

经皮注射羟基磷灰石骨水泥治疗脊柱动脉瘤性骨囊肿

目的

本研究的目的是评估经皮注射羟基磷灰石骨传导水泥对脊柱动脉瘤性骨囊肿患者的治疗效果。

材料和方法

该研究被设计为一项回顾性观察性临床研究。我们纳入了 2013 年至 2020 年间在我们机构被诊断为椎动脉瘤性骨囊肿并接受经皮注射骨传导水泥治疗的患者：“Cerament” ^® （BONESUPPORT AB，隆德，瑞典）。研究了 ABC 治疗和随访的典型临床和放射学特征。

结果

我们的研究包括九名患者，其中两名儿童和七名成人。采用三种不同类型的入路：（3 名患者采用单椎弓根入路；2 名患者采用双椎弓根入路；其余病例采用多入路。VAS 评分从治疗前的 8.5 ± 0.5 降至治疗后的 4.1 ± 0.9。 6 个月的随访中，所有患者对治疗反应良好，没有出现神经系统并发症，疼痛完全消失，并实现了骨硬化作为治疗成功的放射学标志。