Access and barriers to genomic classifiers for breast cancer and prostate cancer in India,International Journal of Cancer

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Access and barriers to genomic classifiers for breast cancer and prostate cancer in India
International Journal of Cancer ( IF 5.7 ) Pub Date : 2023-11-14 , DOI: 10.1002/ijc.34784
Sruthi Ranganathan ₁ , Edward Christopher Dee ₂ , Neha Debnath ₃ , Tej A Patel ₄ , Bhav Jain ₅ , Vedang Murthy ₆

Affiliation

The incidence of cancer in general, including breast and prostate cancer specifically, is increasing in India. Breast and prostate cancers have genomic classifiers developed to guide therapy decisions. However, these genomic classifiers are often inaccessible in India due to high cost. These classifiers may also be less suitable to the Indian population, as data primarily from patients in wealthy Western countries were used in developing these genomic classifiers. In addition to the limitations in using these existing genomic classifiers, developing and validating new genomic classifiers for breast and prostate cancer in India is challenging due to the heterogeneity in the Indian population. However, there are steps that can be taken to address the various barriers that currently exist for accurate, accessible genomic classifiers for cancer in India.

中文翻译：

印度乳腺癌和前列腺癌基因组分类器的获取和障碍

印度癌症的发病率总体呈上升趋势，特别是乳腺癌和前列腺癌。乳腺癌和前列腺癌开发了基因组分类器来指导治疗决策。然而，由于成本高昂，这些基因组分类器在印度通常难以获得。这些分类器也可能不太适合印度人群，因为开发这些基因组分类器时使用的数据主要来自富裕西方国家的患者。除了使用这些现有基因组分类器的局限性之外，由于印度人口的异质性，在印度开发和验证新的乳腺癌和前列腺癌基因组分类器也具有挑战性。然而，可以采取一些措施来解决印度当前在准确、可访问的癌症基因组分类器方面存在的各种障碍。

更新日期：2023-11-14

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