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Hybrids of Polysaccharides and Inorganic Nanoparticles: From Morphological Design to Diverse Biomedical Applications
Accounts of Materials Research ( IF 14.0 ) Pub Date : 2023-11-08 , DOI: 10.1021/accountsmr.3c00172 Nana Zhao 1, 2, 3 , Zhuolong Jiao 1, 2, 3 , Linghui Chen 1, 2, 3 , Zhiwen Liu 1, 2, 3 , Xiaoyi Zhao 1, 2, 3 , Fu-Jian Xu 1, 2, 3
Accounts of Materials Research ( IF 14.0 ) Pub Date : 2023-11-08 , DOI: 10.1021/accountsmr.3c00172 Nana Zhao 1, 2, 3 , Zhuolong Jiao 1, 2, 3 , Linghui Chen 1, 2, 3 , Zhiwen Liu 1, 2, 3 , Xiaoyi Zhao 1, 2, 3 , Fu-Jian Xu 1, 2, 3
Affiliation
As widespread natural polymers with biocompatibility, biodegradability, and bioactivity properties, polysaccharides are considered ideal candidates to fabricate multifunctional platforms for diverse biomedical applications. Inorganic nanoparticles have attracted increased attention due to their favorable physicochemical properties, while further modification is required to realize stability and biocompatibility. Therefore, the fabrication of hybrids of polysaccharides and inorganic nanoparticles into the nanoscale are desirable to facilitate the accumulation of nanohybrids through enhanced permeability and retention effect, which can not only realize complementary functions of individual components, but also produce new and synergistic properties.
中文翻译:
多糖和无机纳米颗粒的杂化物:从形态设计到多样化的生物医学应用
作为具有生物相容性、生物可降解性和生物活性特性的广泛天然聚合物,多糖被认为是制造用于各种生物医学应用的多功能平台的理想候选者。无机纳米颗粒因其良好的理化性质而受到越来越多的关注,但需要进一步修饰以实现稳定性和生物相容性。因此,需要将多糖和无机纳米粒子的杂化物制造成纳米级,通过增强的渗透性和保留效应促进纳米杂化物的积累,这不仅可以实现单个组分的功能互补,而且可以产生新的协同性能。
更新日期:2023-11-08
中文翻译:
多糖和无机纳米颗粒的杂化物:从形态设计到多样化的生物医学应用
作为具有生物相容性、生物可降解性和生物活性特性的广泛天然聚合物,多糖被认为是制造用于各种生物医学应用的多功能平台的理想候选者。无机纳米颗粒因其良好的理化性质而受到越来越多的关注,但需要进一步修饰以实现稳定性和生物相容性。因此,需要将多糖和无机纳米粒子的杂化物制造成纳米级,通过增强的渗透性和保留效应促进纳米杂化物的积累,这不仅可以实现单个组分的功能互补,而且可以产生新的协同性能。