Three new phenolic glycosides (1–3) and a new lignan glycoside (4), together with five known compounds (5–9) were isolated from the ethanol extract of the aerial part of Gaultheria leucocarpa var. yunnanensis (Franch.) T.Z.Hsu & R.C.Fang. Their structures were determined on the basis of spectroscopic techniques, experimental and calculated ECD spectra, acid hydrolysis, and enzymatic hydrolysis experiments. All the isolates were evaluated for their anti-inflammatory and antioxidant activities. Compounds 7 and 8 exhibited inhibitory effects against the LPS-induced production of NO with IC₅₀ of 63.71 and 10.66 μM, respectively, compared to L-NMMA having an IC₅₀ of 6.95 μM. Besides, compound 7 also represented significant DPPH radical scavenging activity with EC₅₀ of 18.75 μM, comparable with vitamin C (EC₅₀ = 15.77 μM).

从Gaultheria leucocarpa var. 地上部分的乙醇提取物中分离出三种新的酚苷 ( 1 – 3 ) 和一种新的木脂素苷 ( 4 )，以及五种已知化合物 ( 5 – 9 )。 yunnanensis (法国) TZHsu & RCFang.它们的结构是根据光谱技术、实验和计算的 ECD 光谱、酸水解和酶水解实验确定的。对所有分离株的抗炎和抗氧化活性进行了评估。与IC ₅₀为6.95 μM的L-NMMA相比，化合物7和8表现出对LPS诱导的NO产生的抑制作用，IC ₅₀分别为63.71和10.66 μM。此外，化合物7还具有显着的DPPH自由基清除活性，EC ₅₀为18.75 μM，与维生素C (EC ₅₀ = 15.77 μM)相当。