Synthetic biodegradable elastomers, such as polyesters and polyurethanes have revolutionized biomedical therapeutic strategies and devices. Driven by innovations in chemical synthesis and processing technologies, a series of biodegradable elastomers and corresponding devices with controllable properties and various functionalities have been developed. In this review, we have summarized the recent progress in synthesis, process technologies, and biomedical applications of biodegradable elastomers. Particular emphasis is on the molecular design for biodegradability, elasticity, and the newly developed functionalities including self-healing, antibacterial, fluorescence, and shape-memory of biodegradable polyesters and polyurethane as well as their corresponding processing strategies. Subsequently, the recent progress of biodegradable elastomers in different biomedical applications is reviewed. A comprehensive conclusion and outlook pointing out emerging research directions, future challenges and potential solutions complete this work.

合成的可生物降解弹性体，例如聚酯和聚氨酯，彻底改变了生物医学治疗策略和设备。在化学合成和加工技术创新的推动下，一系列具有可控性能和多种功能的可生物降解弹性体及相应器件被开发出来。在这篇综述中，我们总结了生物可降解弹性体在合成、工艺技术和生物医学应用方面的最新进展。特别强调生物可降解性、弹性的分子设计，以及生物可降解聚酯和聚氨酯的自修复、抗菌、荧光和形状记忆等新开发的功能及其相应的加工策略。随后，综述了生物可降解弹性体在不同生物医学应用中的最新进展。这项工作完成了全面的结论和展望，指出了新兴的研究方向、未来的挑战和潜在的解决方案。