Introduction

Organophosphorus compounds (OPC) are one of the most commonly used pesticides worldwide and are often misused for suicidal poisoning due to their easy availability. Acute manifestations and management of organophosphorus (OP) poisoning have been reported several times. Organophosphorus-induced delayed neurotoxicity (OPIDN) is a rare delayed presentation of OP poisoning that involves central-peripheral distal axonopathy.

Case presentation

In this study, we report two cases of OPIDN developed after a few weeks of OP poisoning. Clinical features, electrodiagnostic study findings, and rehabilitative measures adopted for the patients and their follow-up have been described in the report.

Discussion

Organophosphorus (OP) poisoning may rarely produce features of delayed neurotoxicity, which may gradually appear after acute cholinergic symptoms. This report shows the importance of considering the delayed presentation of possible OPC toxicity in patients with neurological symptoms and a history of OPC exposure.

中文翻译：

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有机磷中毒致迟发性神经毒性二例报告

介绍

有机磷化合物 (OPC) 是全世界最常用的杀虫剂之一，由于其易于获取，经常被误用于自杀性中毒。有机磷（OP）中毒的急性表现和处理已多次报道。有机磷诱导的迟发性神经毒性 (OPIDN) 是一种罕见的 OP 中毒迟发性表现，涉及中枢-外周远端轴突病变。

案例展示

在这项研究中，我们报告了两例 OP 中毒几周后出现 OPIDN 的病例。报告描述了患者的临床特征、电诊断研究结果、患者采取的康复措施及其随访情况。

讨论

有机磷（OP）中毒很少会产生迟发性神经毒性特征，可能在急性胆碱能症状后逐渐出现。该报告显示了在有神经系统症状和有 OPC 暴露史的患者中考虑可能的 OPC 毒性延迟表现的重要性。