当前位置: X-MOL 学术Molecules › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Rosavin: Research Advances in Extraction and Synthesis, Pharmacological Activities and Therapeutic Effects on Diseases of the Characteristic Active Ingredients of Rhodiola rosea L.
Molecules ( IF 4.2 ) Pub Date : 2023-11-03 , DOI: 10.3390/molecules28217412
Shen Wang 1 , Yanmin Feng 2 , Lin Zheng 2 , Panfeng He 2 , Jingyi Tan 1 , Jinhui Cai 1 , Minhua Wu 3 , Xiaoxia Ye 3
Affiliation  

Rhodiola rosea L. (RRL) is a popular plant in traditional medicine, and Rosavin, a characteristic ingredient of RRL, is considered one of the most important active ingredients in it. In recent years, with deepening research on its pharmacological actions, the clinical application value and demand for Rosavin have been steadily increasing. Various routes for the extraction and all-chemical or biological synthesis of Rosavin have been gradually developed for the large-scale production and broad application of Rosavin. Pharmacological studies have demonstrated that Rosavin has a variety of biological activities, including antioxidant, lipid-lowering, analgesic, antiradiation, antitumor and immunomodulation effects. Rosavin showed significant therapeutic effects on a range of chronic diseases, including neurological, digestive, respiratory and bone-related disorders during in vitro and vivo experiments, demonstrating the great potential of Rosavin as a therapeutic drug for diseases. This paper gives a comprehensive and insightful overview of Rosavin, focusing on its extraction and synthesis, pharmacological activities, progress in disease-treatment research and formulation studies, providing a reference for the production and preparation, further clinical research and applications of Rosavin in the future.

中文翻译:

Rosavin:红景天特征活性成分的提取合成、药理活性及疾病治疗作用研究进展。

红景天 (RRL) 是传统医学中常用的植物,其特征成分罗莎维 (Rosavi) 被认为是其中最重要的活性成分之一。近年来,随着其药理作用研究的不断深入,罗萨维的临床应用价值和需求量不断增加。逐步开发了多种罗萨维的提取和全化学或生物合成路线,以实现罗萨维的规模化生产和广泛应用。药理研究表明,Rosavi具有多种生物活性,包括抗氧化、降脂、镇痛、抗辐射、抗肿瘤和免疫调节等作用。Rosavin在体外和体内实验中显示出对一系列慢性疾病,包括神经、消化、呼吸和骨骼相关疾病的显着治疗效果,展示了Rosavi作为疾病治疗药物的巨大潜力。本文对罗萨维进行了全面深入的综述,重点介绍了罗萨维的提取与合成、药理活性、治病研究和剂型研究进展,为今后罗萨维的生产制备、进一步的临床研究和应用提供参考。 。
更新日期:2023-11-03
down
wechat
bug