Background: Cinnamic acid, derived from Cinnamomum cassia, is a natural compound known for its wide-ranging therapeutic properties and minimal toxicity. Extensive research has demonstrated the diverse biological activities displayed by cinnamic acid derivatives, encompassing their potential as agents against cancer, diabetes, microbial infections, tuberculosis, malaria, and more. Objective: This review aims to provide an overview of the latest applications detailing the biological activity of cinnamic acid derivatives, as documented in patents. Methods: The published patent data underwent a prior screening and selection process based on their relevance and primary focus: the biological activities of cinnamic acid derivatives as potential drugs. Espacenet, USPTO, and Google Patents were used for this selection. Results: Cinnamic acid derivatives demonstrate a range of activities, including anticancer, antibacterial, anti-inflammatory, analgesic, anticholinesterase, and other properties. These biological activities were investigated across different derivatives, emphasizing their pharmacological potential when compared to reference compounds. Conclusions: Despite several patents have explored the biological properties of cinnamic acid derivatives, there has been a lack of a comprehensive review dedicated to this subject. Accordingly, this review aims to facilitate the discovery of new and diverse potential drugs with various therapeutic profiles.

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揭示肉桂酸衍生物的生物应用：专利审查

背景：肉桂酸源自肉桂，是一种天然化合物，以其广泛的治疗特性和最小的毒性而闻名。广泛的研究表明，肉桂酸衍生物具有多种生物活性，包括其作为抗癌、糖尿病、微生物感染、结核病、疟疾等药物的潜力。目的：本综述旨在概述专利中记载的详细介绍肉桂酸衍生物生物活性的最新申请。方法：已发布的专利数据根据其相关性和主要关注点（肉桂酸衍生物作为潜在药物的生物活性）进行了事先筛选和选择过程。Espacenet、USPTO 和 Google 专利用于此选择。结果：肉桂酸衍生物具有一系列活性，包括抗癌、抗菌、抗炎、镇痛、抗胆碱酯酶和其他特性。对不同衍生物的这些生物活性进行了研究，强调了与参考化合物相比它们的药理学潜力。结论：尽管有几项专利探讨了肉桂酸衍生物的生物学特性，但缺乏专门针对该主题的全面综述。因此，本综述旨在促进具有各种治疗特性的新型、多样化的潜在药物的发现。