Froth flotation is an essential processing technique for upgrading low-grade ores. Flotation separation would not be efficient without chemical surfactants (collectors, depressants, frothers, etc.). Depressants play a critical role in the selective separation of minerals in that they deactivate unfavorable mineral surfaces and hinder them from floating into the flotation concentration zone. Pyrite is the most common and challenging sulfide gangue, and its conventional depressants could be highly harmful to nature and humans. Therefore, using available, affordable, eco-friendly polymers to assist or replace hazardous reagents is mandatory for a green transition. Polysaccharide-based (starch, dextrin, carboxymethyl cellulose, guar gum, etc.) polymers are one of the most used biodegradable depressant groups for pyrite depression. Despite the satisfactory flotation results obtained using these eco-friendly depressants, several gaps still need to be addressed, specifically in investigating surface interactions, adsorption mechanisms, and parameters affecting their depression performance. As a unique approach, this review comprehensively discussed previously conducted studies on pyrite depression with polysaccharide-based reagents. Additionally, practical suggestions have been provided for future assessments and developments of polysaccharide-based depressants, which pave the way to green flotation. This robust review also explored the depression efficiency and various adsorption aspects of naturally derived depressants on the pyrite surface to create a possible universal trend for each biodegradable depressant derivative.

泡沫浮选是提质低品位矿石的重要选矿技术。如果没有化学表面活性剂（捕收剂、抑制剂、起泡剂等），浮选分离就不会有效。抑制剂在矿物的选择性分离中起着至关重要的作用，因为它们使不利的矿物表面失活并阻止它们漂浮到浮选浓缩区。黄铁矿是最常见、最具挑战性的硫化物脉石，其传统抑制剂可能对自然和人类造成极大危害。因此，为了实现绿色转型，必须使用可用的、负担得起的、环保的聚合物来辅助或替代危险试剂。多糖基（淀粉、糊精、羧甲基纤维素、瓜尔胶等）聚合物是最常用的黄铁矿抑制生物可降解抑制剂之一。尽管使用这些环保型抑制剂获得了令人满意的浮选结果，但仍需要解决一些差距，特别是在研究表面相互作用、吸附机制和影响其抑制性能的参数方面。作为一种独特的方法，这篇综述全面讨论了以前用多糖试剂进行的黄铁矿抑制研究。此外，还为多糖抑制剂的未来评估和开发提供了实用建议，为绿色浮选铺平了道路。这项强有力的综述还探讨了黄铁矿表面上天然衍生的抑制剂的抑制效率和各种吸附方面，为每种可生物降解的抑制剂衍生物创造了可能的普遍趋势。