用于血红蛋白传感应用的基于光子自旋霍尔效应的超灵敏折射率传感器,Optics & Laser Technology

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用于血红蛋白传感应用的基于光子自旋霍尔效应的超灵敏折射率传感器
Optics & Laser Technology ( IF 4.6 ) Pub Date : 2023-10-17 , DOI: 10.1016/j.optlastec.2023.110183
Lokesh Ahlawat , Kamal Kishor , Ravindra Kumar Sinha

提出了一种基于光子自旋霍尔效应（PSHE）的高灵敏度分层传感器，可检测生物样品折射率的变化。简单而优雅的设计利用表面等离子共振 (SPR) 效应测量血红蛋白浓度。它由 BK7 棱镜、薄金层、血红蛋白分析物层和作为基底的 BK7 玻璃组成。平均角度灵敏度 $（ S_{右} ）$ 经计算发现 $191^{°} / 右我 U$ , $208^{°} / 右我 U$ 和 $171^{°} / 右我 U$ 分别针对低、正常和高血红蛋白浓度。所提出结构的品质因数 (FOM) 为 ${896 右我 U}^{- 1}$ , ${812 右我 U}^{- 1}$ 和 ${3166 右我 U}^{- 1}$ 分别针对低浓度、正常浓度和高浓度的氧合血红蛋白。

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Photonic spin Hall effect-based ultra-sensitive refractive index sensor for haemoglobin sensing applications

A highly sensitive Photonic Spin Hall Effect (PSHE)-based layered sensor is proposed which detects changes in refractive index of biological sample. A simple and elegant design measures haemoglobin concentrations using Surface Plasmon Resonance (SPR) effect. It consists of a BK7 prism, a thin gold layer, an analyte layer of haemoglobin and BK7 glass as the substrate. The average angle sensitivity $(S_{R})$ has been calculated and found to be $191^{°} / R I U$ , $208^{°} / R I U$ and $171^{°} / R I U$ respectively for low, normal and high haemoglobin concentrations. The Figure of Merit (FOM) for the proposed structure is found to be ${896 R I U}^{- 1}$ , ${812 R I U}^{- 1}$ and ${3166 R I U}^{- 1}$ respectively for low, normal and high concentrations of oxygenated haemoglobin.

更新日期：2023-10-17

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