Oxadiazoles and thiadiazoles are malleable heterocycles that have recently generated major interest in the field of medicinal chemistry. Compounds based on these moieties have versatile biological applications such as anticonvulsant, anticancer, antidiabetic, and antioxidant agents. Due to the versatile nature and stability of the oxadiazole and thiadiazole nucleus, medicinal chemists have changed the structural elements of the ring in numerous ways. These compounds have shown significant anticonvulsant effects, demonstrating their potential in the management of epileptic disorders. In this review, we have covered numerous biological pathways and in silico targeted proteins of oxadiazole and thiadiazole derivatives for treating various biological disorders. The data compiled in this article will be helpful for researchers, research scientists, and research chemists who work in the field of drug discovery and drug development.

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揭示 1,3,4-恶二唑和噻二唑的化学性质：全面综述

恶二唑和噻二唑是可延展的杂环化合物，最近在药物化学领域引起了极大的兴趣。基于这些部分的化合物具有多种生物学应用，例如抗惊厥、抗癌、抗糖尿病和抗氧化剂。由于恶二唑和噻二唑核的多功能性和稳定性，药物化学家以多种方式改变了环的结构元素。这些化合物显示出显着的抗惊厥作用，证明了它们在治疗癫痫疾病方面的潜力。在这篇综述中，我们涵盖了恶二唑和噻二唑衍生物的许多生物途径和计算机靶向蛋白，用于治疗各种生物疾病。本文中汇编的数据将对从事药物发现和药物开发领域工作的研究人员、研究科学家和研究化学家有所帮助。