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右美托咪定通过BDNF/TrkB/CREB信号通路促进缺氧缺血新生大鼠海马神经发生,从而减轻认知障碍
CNS Neuroscience & Therapeutics ( IF 4.8 ) Pub Date : 2023-10-13 , DOI: 10.1111/cns.14486 Xiaohui Chen 1 , Andi Chen 1 , Jianjie Wei 1 , Yongxin Huang 1 , Jianhui Deng 1 , Pinzhong Chen 1 , Yanlin Yan 1 , Mingxue Lin 1 , Lifei Chen 1 , Jiuyun Zhang 2 , Zhibin Huang 1 , Xiaoqian Zeng 1 , Cansheng Gong 1 , Xiaochun Zheng 1, 2, 3
Affiliation
据报道,右美托咪定 (DEX) 可减轻新生儿缺氧缺血性脑损伤 (HIBD)。本研究旨在探讨 DEX 是否通过 BDNF/TrkB/CREB 信号通路促进海马神经发生来改善 HIBD 新生大鼠的认知障碍。
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