Podophyllotoxin is a natural product with interesting medicinal and agricultural values. Herein, new podophyllotoxin analogues with new skeletons isolated from plants are listed, as well as the total synthesis, structural modifications, biological activity and structure–activity relationships of podophyllotoxin and its derivatives. Hopefully, this review will serve as a reference for further research on podophyllotoxin and its derivatives.

中文翻译：

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鬼臼毒素的化学和生物学：最新进展

鬼臼毒素是一种天然产物，具有有趣的药用和农业价值。本文列出了从植物中分离得到的具有新骨架的新鬼臼毒素类似物，以及鬼臼毒素及其衍生物的全合成、结构修饰、生物活性和构效关系。希望本文的综述能为鬼臼毒素及其衍生物的进一步研究提供参考。