Data Storage Using DNA,Advanced Materials

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Data Storage Using DNA
Advanced Materials ( IF 27.4 ) Pub Date : 2023-10-06 , DOI: 10.1002/adma.202307499
Shaopeng Wang ₁ , Xiuhai Mao ₁ , Fei Wang ₂ , Xiaolei Zuo _{1,

2} , Chunhai Fan _{1,

2}

Affiliation

The exponential growth of global data has outpaced the storage capacities of current technologies, necessitating innovative storage strategies. DNA, as a natural medium for preserving genetic information, has emerged as a highly promising candidate for next-generation storage medium. Storing data in DNA offers several advantages, including ultrahigh physical density and exceptional durability. Facilitated by significant advancements in various technologies, such as DNA synthesis, DNA sequencing, and DNA nanotechnology, remarkable progress has been made in the field of DNA data storage over the past decade. However, several challenges still need to be addressed to realize practical applications of DNA data storage. In this review, the processes and strategies of in vitro DNA data storage are first introduced, highlighting recent advancements. Next, a brief overview of in vivo DNA data storage is provided, with a focus on the various writing strategies developed to date. At last, the challenges encountered in each step of DNA data storage are summarized and promising techniques are discussed that hold great promise in overcoming these obstacles.

中文翻译：

使用 DNA 进行数据存储

全球数据的指数级增长已经超过了当前技术的存储容量，因此需要创新的存储策略。 DNA 作为保存遗传信息的天然介质，已成为下一代存储介质的极有前途的候选者。在 DNA 中存储数据具有多种优势，包括超高物理密度和卓越的耐用性。过去十年，在DNA合成、DNA测序和DNA纳米技术等各种技术的重大进步的推动下，DNA数据存储领域取得了显着进展。然而，要实现 DNA 数据存储的实际应用，仍然需要解决一些挑战。在这篇综述中，首先介绍了体外 DNA 数据存储的流程和策略，重点介绍了最新进展。接下来，简要概述体内 DNA 数据存储，重点介绍迄今为止开发的各种写入策略。最后，总结了 DNA 数据存储每个步骤中遇到的挑战，并讨论了有望克服这些障碍的有前途的技术。

更新日期：2023-10-06

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