Herein, an operationally simple protocol for the ex-situ generation of the toxic and volatile disulfide, CF₃SSCF₃, from the readily available and cost-efficient Langlois reagent is reported. Among the trifluoromethythiolations reaction studied, application of this disulfide in a Cu-catalyzed coupling with aryl boronic acids is disclosed, showing good to excellent yields of trifluoromethylthio-substituted aryl products.

中文翻译：

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双(三氟甲基)二硫化物的异位生成及其在三氟甲硫基化反应中的应用

在此，报道了一种操作简单的方案，用于从易于获得且具有成本效益的朗格卢瓦试剂中异位生成有毒且挥发性的二硫化物CF ₃ SSCF _{3 。}在所研究的三氟甲硫基化反应中，公开了这种二硫化物在铜催化的与芳基硼酸的偶联中的应用，显示出三氟甲硫基取代的芳基产物的良好至优异的产率。