Pentafluorobenzene (PFB) represents a class of aromatic fluorine compounds employed exclusively across a spectrum of chemical and biological applications. PFBs are credited with developing various chemical synthesis techniques, networks and biopolymers, bioactive materials, and targeted drug delivery systems. The first part of this review delves into recent developments in PFB-derived molecules for diagnostic purposes. In the latter segment, PFB’s role in the domain of theragnostic applications is discussed. The review elucidates different mechanisms and interaction strategies applied in leveraging PFBs to formulate diagnostic and theragnostic tools, substantiated by proper examples. The utilization of PFBs emerges as an enabler, facilitating manifold reactions, improving materials’ properties, and even opening avenues for explorative research.

中文翻译：

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五氟苯：在诊断和治疗方面的应用前景

五氟苯 (PFB) 代表一类专门用于一系列化学和生物应用的芳香族氟化合物。PFB 因开发各种化学合成技术、网络和生物聚合物、生物活性材料和靶向药物输送系统而受到赞誉。本综述的第一部分深入研究了用于诊断目的的 PFB 衍生分子的最新进展。在后一部分中，讨论了 PFB 在治疗诊断应用领域中的作用。该综述阐明了利用 PFB 制定诊断和治疗工具的不同机制和交互策略，并通过适当的示例进行了证实。PFB 的利用成为一种推动因素，促进多种反应，改善材料性能，甚至为探索性研究开辟途径。