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A review of indigenous knowledge and ethnopharmacological significance of African Copaiba Balsam Tree, Daniellia oliveri (Fabaceae)
Heliyon ( IF 3.4 ) Pub Date : 2023-09-15 , DOI: 10.1016/j.heliyon.2023.e20228
Fatai Oladunni Balogun 1 , Abdulwakeel Ayokun-Nun Ajao 2 , Saheed Sabiu 1
Affiliation  

Daniellia oliveri has found its indigenous relevance in the management of diseases including but not limited to diabetes mellitus, tuberculosis, fever, ulcers, pain, worm manifestation, pneumonia, skin ailments, infectious diseases, sickle cell anaemia, hence, a review of its indigenous knowledge, ethnopharmacological and nutritional benefits was undertaken. Information used for the review was sourced from popular scientific databases (Google Scholar, PubMed, Science Direct, Web of Science, BioMed Central, JSTOR, African Plant, Global Biodiversity Information and others), conference proceedings, dissertations or theses, chapters in books, edited books, and journal collections. The materials obtained from 121 scientific documents targeting majorly between 1994 and 2023 established the presence of major secondary metabolites (such as polyphenols, flavonoids, saponins, alkaloids, etc.), minerals (e.g., sodium, potassium, phosphorus, selenium, calcium, magnesium, etc.), vitamins (beta-carotene, thiamine, riboflavin, niacin, ascorbic acid, etc.), and nutrients (crude protein, moisture, dry matter, ether, carbohydrates, and energy). Literature also lent credence to the preliminary safety profiles of the plant and its pharmacological potentials as analgesic, antinociceptive, antioxidant, antidiabetic, antidiarrhoeal, anthelmintic, anti-inflammatory, antimelanogenesis, antimicrobial, antiplasmodial, antisickling, cardiotoxic, cytotoxic, and neuroprotective agents. While the review is majorly limited to Africa particularly western countries (such as Nigeria, Burkina Faso, Mali, Ghana, Togo, and Benin) and the plant is found to be largely underutilized, it is evident that limited information exists on the in vivo pharmacological evaluation, bioactive compounds identification, and there is a lack of preclinical and clinical trials for possible drug development. Based on the aforementioned, it is hoped that further research studies geared toward providing insights into the established grey areas (such as traditional use investigation, targeted or assay-guided compounds identification, and preclinical and clinical studies) are necessary in order to fully explore the therapeutic, nutritional, and economic benefits of the plant.

中文翻译:


非洲苦配巴香脂树 Daniellia oliveri(豆科)的本土知识和民族药理学意义综述



Daniellia oliveri 发现其在疾病管理中的本土相关性,包括但不限于糖尿病、结核病、发烧、溃疡、疼痛、蠕虫表现、肺炎、皮肤病、传染病、镰状细胞性贫血,因此,对其本土病进行了审查知识、民族药理学和营养益处进行了研究。用于审查的信息来自流行的科学数据库(Google Scholar、PubMed、Science Direct、Web of Science、BioMed Central、JSTOR、非洲植物、全球生物多样性信息等)、会议记录、学位论文、书籍章节、编辑书籍和期刊集。从 1994 年至 2023 年间主要针对的 121 份科学文献中获得的材料证实了主要次生代谢物(如多酚、类黄酮、皂苷、生物碱等)、矿物质(如钠、钾、磷、硒、钙、镁)的存在。等)、维生素(β-胡萝卜素、硫胺素、核黄素、烟酸、抗坏血酸等)、营养素(粗蛋白、水分、干物质、乙醚、碳水化合物、能量)。文献还证实了该植物的初步安全性及其作为镇痛、抗伤害、抗氧化剂、抗糖尿病、止泻、驱虫、抗炎、抗黑色素生成、抗菌、抗疟原虫、抗镰刀、心脏毒性、细胞毒性和神经保护剂的药理潜力。 虽然审查主要限于非洲特别是西方国家(如尼日利亚、布基纳法索、马里、加纳、多哥和贝宁),并且发现该植物基本上未得到充分利用,但显然有关体内药理学的信息有限。评估、生物活性化合物鉴定,并且缺乏可能的药物开发的临床前和临床试验。基于上述内容,希望有必要进行进一步的研究,以深入了解已建立的灰色地带(例如传统用途调查、靶向或测定指导化合物鉴定以及临床前和临床研究),以便充分探索该植物的治疗、营养和经济效益。
更新日期:2023-09-15
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