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A review of indigenous knowledge and ethnopharmacological significance of African Copaiba Balsam Tree, Daniellia oliveri (Fabaceae)
Heliyon ( IF 3.4 ) Pub Date : 2023-09-15 , DOI: 10.1016/j.heliyon.2023.e20228
Fatai Oladunni Balogun 1 , Abdulwakeel Ayokun-Nun Ajao 2 , Saheed Sabiu 1
Affiliation  

Daniellia oliveri has found its indigenous relevance in the management of diseases including but not limited to diabetes mellitus, tuberculosis, fever, ulcers, pain, worm manifestation, pneumonia, skin ailments, infectious diseases, sickle cell anaemia, hence, a review of its indigenous knowledge, ethnopharmacological and nutritional benefits was undertaken. Information used for the review was sourced from popular scientific databases (Google Scholar, PubMed, Science Direct, Web of Science, BioMed Central, JSTOR, African Plant, Global Biodiversity Information and others), conference proceedings, dissertations or theses, chapters in books, edited books, and journal collections. The materials obtained from 121 scientific documents targeting majorly between 1994 and 2023 established the presence of major secondary metabolites (such as polyphenols, flavonoids, saponins, alkaloids, etc.), minerals (e.g., sodium, potassium, phosphorus, selenium, calcium, magnesium, etc.), vitamins (beta-carotene, thiamine, riboflavin, niacin, ascorbic acid, etc.), and nutrients (crude protein, moisture, dry matter, ether, carbohydrates, and energy). Literature also lent credence to the preliminary safety profiles of the plant and its pharmacological potentials as analgesic, antinociceptive, antioxidant, antidiabetic, antidiarrhoeal, anthelmintic, anti-inflammatory, antimelanogenesis, antimicrobial, antiplasmodial, antisickling, cardiotoxic, cytotoxic, and neuroprotective agents. While the review is majorly limited to Africa particularly western countries (such as Nigeria, Burkina Faso, Mali, Ghana, Togo, and Benin) and the plant is found to be largely underutilized, it is evident that limited information exists on the in vivo pharmacological evaluation, bioactive compounds identification, and there is a lack of preclinical and clinical trials for possible drug development. Based on the aforementioned, it is hoped that further research studies geared toward providing insights into the established grey areas (such as traditional use investigation, targeted or assay-guided compounds identification, and preclinical and clinical studies) are necessary in order to fully explore the therapeutic, nutritional, and economic benefits of the plant.

中文翻译:


非洲古巴香脂树 Daniellia oliveri (豆科) 的土著知识和民族药理学意义综述



Daniellia oliveri 发现其在疾病管理中的本土相关性,包括但不限于糖尿病、肺结核、发烧、溃疡、疼痛、蠕虫表现、肺炎、皮肤病、传染病、镰状细胞贫血,因此,对其本土知识、民族药理学和营养益处进行了审查。用于审查的信息来自流行的科学数据库(Google Scholar、PubMed、Science Direct、Web of Science、BioMed Central、JSTOR、African Plant、Global Biodiversity Information 等)、会议论文、学位论文或论文、书籍章节、编辑的书籍和期刊收藏。从 121 份主要针对 1994 年至 2023 年的科学文献中获得的材料确定了主要次生代谢物(如多酚、类黄酮、皂苷、生物碱等)、矿物质(如钠、钾、磷、硒、钙、镁等)、维生素(β-胡萝卜素、硫胺素、核黄素、烟酸、抗坏血酸等)和营养物质(粗蛋白、水分、干物质、醚、碳水化合物和能量)。文献还证实了该植物的初步安全性及其作为镇痛、抗伤害、抗氧化、抗糖尿病、止泻、驱虫、抗炎、抗黑色素生成、抗菌、抗疟原虫、抗镰状细胞、心脏毒性、细胞毒性和神经保护剂的药理潜力。 虽然该综述主要限于非洲尤其是西方国家(如尼日利亚、布基纳法索、马里、加纳、多哥和贝宁),并且发现该植物在很大程度上未得到充分利用,但很明显,关于体内药理学评价、生物活性化合物鉴定的信息有限,并且缺乏可能的药物开发的临床前和临床试验。基于上述内容,希望有必要进行进一步的研究,以提供对已建立灰色区域的见解(例如传统使用调查、靶向或分析指导的化合物鉴定,以及临床前和临床研究),以充分探索植物的治疗、营养和经济效益。
更新日期:2023-09-15
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