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The effect of novel 3R,6R-bis (4-hydroxy benzyl) piperazine-2,5-dione (BHBPPD) derivatives on the expression of caspases in gastric cancer: A molecular docking and dynamics simulation
Arabian Journal of Chemistry ( IF 5.3 ) Pub Date : 2023-09-14 , DOI: 10.1016/j.arabjc.2023.105260 Fatth Rohani , Seyyed Hossein Khadem Hosseini , Delaram Hosseini , Sahar Bahaloo , Shamim Ghiabi , Ehsan Heidari Soureshjani , Sadegh Farhadian , Mohammad Abdolvand , Farhang Tirgir
Arabian Journal of Chemistry ( IF 5.3 ) Pub Date : 2023-09-14 , DOI: 10.1016/j.arabjc.2023.105260 Fatth Rohani , Seyyed Hossein Khadem Hosseini , Delaram Hosseini , Sahar Bahaloo , Shamim Ghiabi , Ehsan Heidari Soureshjani , Sadegh Farhadian , Mohammad Abdolvand , Farhang Tirgir
2,5-Diketopiperazines show remarkable pharmaceutical potential. Growing cancer cases drive novel drug research, focusing on synthesizing an anticancer agent for gastric cells.
中文翻译：
新型3R,6R-双(4-羟基苄基)哌嗪-2,5-二酮(BHPPPD)衍生物对胃癌中caspase表达的影响：分子对接和动力学模拟
2,5-二酮哌嗪显示出显着的药物潜力。不断增长的癌症病例推动了新药研究，重点是合成胃细胞抗癌剂。
更新日期：2023-09-14
中文翻译：
新型3R,6R-双(4-羟基苄基)哌嗪-2,5-二酮(BHPPPD)衍生物对胃癌中caspase表达的影响：分子对接和动力学模拟
2,5-二酮哌嗪显示出显着的药物潜力。不断增长的癌症病例推动了新药研究，重点是合成胃细胞抗癌剂。
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