The versatile manipulation of cross-scale droplets is essential in many fields. Magnetic excitation is widely used for droplet manipulation due to its distinguishing merits. However, facile magnetic actuation strategies are still lacked to realize versatile multiscale droplet manipulation. Here, a type of magnetically actuated Janus origami robot is readily fabricated for versatile cross-scale droplet manipulation including three-dimensional transport, merging, splitting, dispensing and release of daughter droplets, stirring and remote heating. The robot allows untethered droplet manipulation from ~3.2 nL to ~51.14 μL. It enables splitting of droplet, precise dispensing (minimum of ~3.2 nL) and release (minimum of ~30.2 nL) of daughter droplets. The combination of magnetically controlled rotation and photothermal properties further endows the robot with the ability to stir and heat droplets remotely. Finally, the application of the robot in polymerase chain reaction (PCR) is explored. The extraction and purification of nucleic acids can be successfully achieved.

跨尺度液滴的多功能操纵在许多领域都至关重要。磁激励由于其独特的优点而被广泛用于液滴操纵。然而，仍然缺乏简便的磁驱动策略来实现多功能的多尺度液滴操纵。在这里，一种磁驱动的 Janus 折纸机器人很容易制造出来，用于多功能的跨尺度液滴操纵，包括三维传输、合并、分裂、分配和释放子液滴、搅拌和远程加热。该机器人允许不受束缚的液滴操纵，范围从约 3.2 nL 到约 51.14 μL。它能够分裂液滴、精确分配（最小~3.2 nL）和释放（最小~30.2 nL）子液滴。磁控旋转和光热特性的结合进一步赋予机器人远程搅拌和加热液滴的能力。最后探讨了机器人在聚合酶链式反应（PCR）中的应用。可以成功实现核酸的提取和纯化。