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A study on the oxidation of 1-(4-chlorophenyl) pyrazolidin-3-one to 1-(4-chlorophenyl)-3-pyrazolol by oxygen
Journal of Chemical Technology and Biotechnology ( IF 2.8 ) Pub Date : 2023-09-04 , DOI: 10.1002/jctb.7510
Bao‐Guang Zhu 1 , Yu‐Cheng Jiang 1 , Lin‐Peng Song 1 , Xiang‐Li Long 1
Affiliation  

Pyraclostrobin manifests a bright promise in agriculture with the characteristics of a broad spectrum, high efficiency, low toxicity, non-target biosafety, and friendliness to users and the environment due to its ability to inhibit mitochondrial respiration in a novel mode of action. 1-(4-chlorophenyl)-3-pyrazolol is an essential intermediate for the preparation of pyraclostrobin. The commercial technology for the production of 1-(4-chlorophenyl)-3-pyrazolol by oxidizing 1-(4-chlorophenyl)pyrazolidan-3-one with H2O2 in strong an alkali solution is risky and not friendly to the environment.

中文翻译:


氧气氧化1-(4-氯苯基)吡唑烷-3-酮生成1-(4-氯苯基)-3-吡唑醇的研究



唑菌胺酯以一种新颖的作用方式抑制线粒体呼吸,具有广谱、高效、低毒、非靶点生物安全、对使用者和环境友好等特点,在农业领域展现出广阔的前景。 1-(4-氯苯基)-3-吡唑醇是制备唑菌胺酯的重要中间体。 H 2 O 2 氧化 1-(4-氯苯基)吡唑烷-3-酮生产 1-(4-氯苯基)-3-吡唑醇的商业化技术强碱溶液存在风险且对环境不友好。
更新日期:2023-09-04
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