High atomic utilization of single atom catalysts (SACs) have the advantages of high catalytic performance and high selectivity. The characteristics of “independent active site” and “easy recycling” of heterogeneous catalysts can effectively solve the deficiencies of precious-metal catalysts for energy conversion applications. However, to get the full advantages of SACs, the role of anchoring sites and supports is critically significant. The anchoring supports enhanced the stability of isolated atoms as well as affected its electronic assembly, thereby affecting the catalytic performance. MXenes are emergent new 2D materials with the characteristics of high specific surface area, adjustable band gap, good conductivity and rich chelating sites, an ideal support material for SACs. This paper briefly summarized the structural characteristics of MXene, reviewed the preparation strategies of MXene-based SACs, and emphasized the energy conversion applications of MXene-based SACs by discussing the small molecular reactions, including O₂/H₂ evolution reaction, oxygen/CO₂/N₂ reduction reactions as well as bi-functional SACs for the water-splitting and rechargeable metal-air batteries. Finally, the current challenges and opportunities are summarized in synthesis of MXene-based SACs and energy conversion applications.

高原子利用率的单原子催化剂（SAC）具有催化性能高、选择性高的优点。多相催化剂“独立活性位点”和“易于回收利用”的特点可以有效解决贵金属催化剂在能源转换应用中的不足。然而，为了充分发挥 SAC 的优势，锚定位点和支撑物的作用至关重要。锚定载体增强了孤立原子的稳定性并影响其电子组装，从而影响催化性能。MXenes是新兴的新型二维材料，具有高比表面积、可调节带隙、良好的导电性和丰富的螯合位点等特点，是SACs的理想支撑材料。本文简单总结了MXene的结构特点，₂ /H ₂析出反应、氧/CO ₂ /N ₂还原反应以及用于水分解和可充电金属-空气电池的双功能SAC。最后，总结了当前基于 MXene 的 SAC 合成和能量转换应用面临的挑战和机遇。