Chinese Chemical Letters ( IF 9.4 ) Pub Date : 2023-08-31 , DOI: 10.1016/j.cclet.2023.109008 Yubin Ding , Jiaxin Wang , Ruinan Wang , Yongshu Xie
Saccharide sensing is a very meaningful research topic as saccharides are involved in many biological activities. However, it is challenging to design molecular sensors for saccharides because this family of compounds is hydromimetic in aqueous solutions and shares a similar chemical structure. In this review, research progress in the development of porphyrin-based saccharide sensors is described with representative examples. We focus on using porphyrin as the signal reporter because porphyrins exhibit unique advantages in high chemical stability, long emission wavelength, and multiple structural modification strategies. Reported literature results have been classified into mainly two sections according to the general working principles of the porphyrin sensor molecules. In the first section, recognition unit, design strategy and sensing performance of traditional porphyrin-based selective saccharide sensors are discussed. While in the second section, development of porphyrin-based sensor arrays for pattern recognition of saccharides has been summarized. Looking through the design strategy and sensing performance of reported achievements, it is reasonable to anticipate a bright future for designing practical porphyrin-based saccharide sensors.
中文翻译:
开发用于糖类识别的基于卟啉的荧光传感器和传感器阵列
糖类传感是一个非常有意义的研究课题,因为糖类参与许多生物活动。然而,设计糖类分子传感器具有挑战性,因为该类化合物在水溶液中是拟水性的,并且具有相似的化学结构。本文综述了基于卟啉的糖类传感器的研究进展,并结合代表性的例子进行了介绍。我们专注于使用卟啉作为信号报道分子,因为卟啉在高化学稳定性、长发射波长和多种结构修饰策略方面表现出独特的优势。根据卟啉传感器分子的一般工作原理,已报道的文献结果主要分为两部分。在第一部分中,讨论了传统的基于卟啉的选择性糖传感器的识别单元、设计策略和传感性能。在第二部分中,总结了用于糖类模式识别的基于卟啉的传感器阵列的发展。纵观已报道的设计策略和传感性能,可以合理地预见设计实用的基于卟啉的糖类传感器的光明前景。