Syringin is found in the root of Acanthopanax senticosus (Rupr. Maxim.) Harms and belongs to the lignin chemical compound with many biological activities. In this study, we employed commercially available starting materials and accomplished the total synthesis of syringin in 5 steps with an overall yield of 58%. Palladium-catalyzed C(O)–C bond activation and subsequent cross coupling reaction is the key to construct syringin and its natural analogues.

中文翻译：

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通过芳基酮的 CC 键活化全合成丁香苷及其天然类似物†

紫丁香苷存在于刺五加(Rupr. Maxim.) 的根中，属于木质素化合物，具有多种生物活性。在本研究中，我们采用市售起始原料，分5步完成了丁香苷的全合成，总收率为58%。钯催化的C(O)-C键活化和随后的交叉偶联反应是构建丁香苷及其天然类似物的关键。