In this paper, by a simple hydrothermal method vertically aligned ZnO nanorod arrays were grown on the carbon fiber paper (CFP) and then through a facile chemical bath deposition method CuO nanosheets were loaded on ZnO nanorod arrays, following by thermal spraying method, carboxylated carbon nanotubes (CCNTs) were successfully integrated with CuO/ZnO@CFP to form a binder-free CuO/ZnO-CCNT@CFP sensor. The sensor shows enhanced sensing activity for baicalein and luteolin determination due to the improved structural integration and synergism of different electrode material components. Remarkably, the CuO/ZnO-CCNT@CFP sensor showed good linear relationships over wide concentration ranges of 0.03–0.70 µM and 0.70–20 µM for baicalein and 0.03–0.45 µM and 0.45–8.5 µM for luteolin detection, with the detection limits of 1.7 nM for baicalein and 0.5 nM for luteolin, respectively. More importantly, the CuO/ZnO-CCNT@CFP sensor was utilized in the simultaneous determination of baicalein and luteolin, delivering linear ranges of 0.4–14 µM (baicalein) and 0.2–6 µM (luteolin) with the limit of detection of 0.05 µM and 0.03 µM, respectively. In addition, the developed CuO/ZnO-CCNT@CFP electrode was further investigated to detect baicalein and luteolin in traditional herbal medicine samples, showing satisfied results in comparison with analytic results from high performance liquid chromatography.

Graphical abstract

中文翻译：

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基于CuO/ZnO-CCNT三元纳米复合材料修饰的碳纤维纸电极高效同时测定黄芩素和木犀草素

本文通过简单的水热法在碳纤维纸（CFP）上生长垂直排列的 ZnO 纳米棒阵列，然后通过简便的化学浴沉积方法将 CuO 纳米片负载在 ZnO 纳米棒阵列上，然后通过热喷涂方法，羧化碳纳米管（CCNT）成功与 CuO/ZnO@CFP 集成，形成无粘合剂的 CuO/ZnO-CCNT@CFP 传感器。由于不同电极材料成分的结构集成和协同作用得到改善，该传感器在黄芩素和木犀草素测定方面表现出增强的传感活性。值得注意的是，CuO/ZnO-CCNT@CFP 传感器在黄芩素检测 0.03–0.70 µM 和 0.70–20 µM 以及木犀草素检测 0.03–0.45 µM 和 0.45–8.5 µM 的宽浓度范围内表现出良好的线性关系，检测限为黄芩素为 1.7 nM，0。木犀草素分别为 5 nM。更重要的是，CuO/ZnO-CCNT@CFP传感器用于同时测定黄芩素和木犀草素，线性范围为0.4–14 µM（黄芩素）和0.2–6 µM（木犀草素），检测限为0.05 µM和 0.03 µM，分别。此外，进一步研究了所开发的CuO/ZnO-CCNT@CFP电极对传统草药样品中黄芩素和木犀草素的检测，与高效液相色谱的分析结果相比，显示出满意的结果。

图形概要