Abstract

The presented modification of the method of local optical tomography makes it possible to study the dynamic processes of subcellular structures of native nerve cells. The advantage of this approach is that it is possible to analyze the dynamics of the distribution of neuron structures at a point or area of interest inside the cell without performing a complete reconstruction of the cell image. It has been proved that it becomes possible to determine the dimensions, the cell area of interest, and the coordinates of subcellular structures for further study of their dynamics. In this modification, the method of local tomography could be used to study both cells and cellular structures, because it is not necessary to probe a full field of view. Local probing of the region of interest during the functioning of the nerve cell will, first, reduce the time of data recording for obtaining local tomograms and second, provide the opportunity to explore the dynamics of several regions inside the cell at the same time.

中文翻译：

---

神经细胞的局部光学断层扫描

摘要

对局部光学断层扫描方法的改进使得研究天然神经细胞亚细胞结构的动态过程成为可能。这种方法的优点是可以分析细胞内感兴趣的点或区域的神经元结构分布的动态，而无需对细胞图像进行完整的重建。已经证明，可以确定亚细胞结构的尺寸、感兴趣的细胞区域和坐标，以进一步研究其动力学。在这种修改中，局部断层扫描方法可用于研究细胞和细胞结构，因为不需要探测整个视野。在神经细胞发挥作用期间对感兴趣区域进行局部探测，首先，