The skin is known to be the largest organ in the human body, while also being exposed to environmental elements. This indicates that skin is highly susceptible to physical infliction, as well as damage resulting from medical conditions such as obesity and diabetes. The wound management costs in hospitals and clinics are expected to rise globally over the coming years, which provides pressure for more wound healing aids readily available in the market. Recently, nanomaterials have been gaining traction for their potential applications in various fields, including wound healing. Here, we discuss various inorganic nanoparticles such as silver, titanium dioxide, copper oxide, cerium oxide, MXenes, PLGA, PEG, and silica nanoparticles with their respective roles in improving wound healing progression. In addition, organic nanomaterials for wound healing such as collagen, chitosan, curcumin, dendrimers, graphene and its derivative graphene oxide were also further discussed. Various forms of nanoparticle drug delivery systems like nanohydrogels, nanoliposomes, nanofilms, and nanoemulsions were discussed in their function to deliver therapeutic agents to wound sites in a controlled manner.

众所周知，皮肤是人体最大的器官，同时也暴露在环境因素中。这表明皮肤非常容易受到身体伤害以及肥胖和糖尿病等医疗状况造成的损害。未来几年，全球医院和诊所的伤口管理成本预计将上升，这给市场上提供更多伤口愈合辅助工具带来了压力。最近，纳米材料因其在伤口愈合等各个领域的潜在应用而受到关注。在这里，我们讨论各种无机纳米颗粒，如银、二氧化钛、氧化铜、氧化铈、MXenes、PLGA、PEG 和二氧化硅纳米颗粒，以及它们在改善伤口愈合进程中各自的作用。此外，还进一步讨论了胶原蛋白、壳聚糖、姜黄素、树枝状聚合物、石墨烯及其衍生物氧化石墨烯等用于伤口愈合的有机纳米材料。讨论了各种形式的纳米颗粒药物递送系统，如纳米水凝胶、纳米脂质体、纳米膜和纳米乳液，讨论了它们以受控方式将治疗剂递送至伤口部位的功能。