This manuscript presents a comprehensive performance analysis of a proposed Kretschman configured tantalum disulfide (TaS₂)–mediated symmetric long-range surface plasmon resonance (SLRSPR) biosensor. The sensor performance is optimized and compared for different metals (Au, Ag, and Al) and four dielectric buffer layers, DBLs (LiF, Teflon, Cytop and MgF₂), to explore the best suited metal and DBL. The 27-nm thickness of Al and 1000 nm of LiF has demonstrated the best performance by achieving smaller full width at half maximum (FWHM = 0.03 Deg.), higher values of detection accuracy (DA = 33.33 1/Deg.), imaging figure of merit (IFOM = 431,933.34 Deg.⁻¹ RIU⁻¹) and imaging sensitivity (S_img. = 12,958 RIU⁻¹) for the proposed SLRSPR biosensor. The proposed LRSPR sensor show 45.32 times higher S_img., 181.03 times higher IFOM and 4.37 times higher DA than conventional SPR (CSPR) sensor. Furthermore, it exhibits 6.76 times higher S_img., 13.52 times higher IFOM and 2 times higher DA than the conventional LRSPR (CLRSPR) sensor. The proposed SLRSPR biosensor shows the highest PD (401.5 nm), indicating deep analyte sensing. The work presented here highlights the significant potential of the proposed SLRSPR biosensor in biomedical applications that require highly accurate and sensitive refractive index sensing.

本手稿对拟议的 Kretschman 配置的二硫化钽 (TaS ₂ ) 介导的对称长程表面等离子共振 (SLRSPR) 生物传感器进行了全面的性能分析。_{针对不同金属（Au、Ag 和 Al）和四个介电缓冲层 DBL（LiF、Teflon、Cytop 和 MgF 2} ）对传感器性能进行了优化和比较，以探索最适合的金属和 DBL 。27 nm 厚度的 Al 和 1000 nm LiF 通过实现更小的半峰全宽（FWHM = 0.03 Deg.）、更高的检测精度值（DA = 33.33 1/Deg.）、成像图而展示了最佳性能优点 (IFOM = 431,933.34 Deg. ^-1 RIU ^-1 ) 和成像灵敏度 ( S _{img .} = 12,958 RIU ^-1 ) 对于所提出的 SLRSPR 生物传感器。所提出的 LRSPR 传感器显示S _{img高出 45.32 倍。}，比传统SPR（CSPR）传感器高181.03倍IFOM和4.37倍DA。此外，它的S _img提高了 6.76 倍_。，比传统 LRSPR (CLRSPR) 传感器高 13.52 倍 IFOM 和 2 倍 DA。所提出的 SLRSPR 生物传感器显示出最高的 PD (401.5 nm)，表明深层分析物传感。这里介绍的工作强调了所提出的 SLRSPR 生物传感器在需要高精度和灵敏折射率传感的生物医学应用中的巨大潜力。