An environmental friendly, fast, easy, inexpensive and dispersive-solvent-free liquid–liquid microextraction (LLME) based on pH-switchable hydrophobic deep eutectic solvent (HDES) procedure was developed and combined with high performance liquid chromatography–ultraviolet (HPLC − UV) detection for the extraction and analysis of triazine herbicides in water samples. In this method, 10 different DESs were prepared and then their pH-switchability was investigated. DESs that could be switched with pH were employed for separation and preconcentration of triazine herbicides in water samples. In this method, dispersing the extractant phase in the aqueous solution and subsequent phase separation is done only by changing the pH. Important parameters affecting extraction, such as type of DES and its volume, concentration of KOH, volume of HCL, effect of salt and extraction time were investigated and optimum conditions were obtained. In optimized conditions, the values of relative standard deviations (RSDs) for intra-day and inter-day of the procedure based on seven replicate analysis of 100 μg L^–1 of triazines in water samples were 1.9–4.4 and 2.7–6.2%, respectively. The calibration graphs were linear ranging from 0.5 to 350 μg L^–1 with correlation coefficients (r²) better than 0.990. The limit of detections (LODs) and limit of quantifications (LOQs) were 0.2–0.5 and 0.5–1.5 μg L^–1, respectively. The relative recoveries (RRs) of real water samples which have been spiked with different levels of triazines were 91–107.8%.

开发了一种基于 pH 可切换的疏水性低共熔溶剂 (HDES) 程序的环保、快速、简单、廉价且无分散溶剂的液-液微萃取 (LLME)，并将其与高效液相色谱-紫外 (HPLC − UV) 相结合。 ）用于水样中三嗪类除草剂的提取和分析的检测。在该方法中，制备了 10 种不同的 DES，然后研究了它们的 pH 切换能力。采用可随 pH 值切换的 DES 来分离和富集水样中的三嗪除草剂。在该方法中，仅通过改变pH值来将萃取剂相分散在水溶液中并随后进行相分离。影响萃取的重要参数，例如 DES 类型及其体积、KOH 浓度、HCL 体积、考察了盐和提取时间的影响，确定了最佳条件。在优化条件下，程序日内和日间的相对标准偏差 (RSD) 值基于 100 μg L-1 的七次重复分析^{水样中三嗪的-1}含量分别为1.9-4.4%和2.7-6.2%。校准图在 0.5 至 350 µg L ^–1范围内呈线性，相关系数 (r ² ) 优于 0.990。检测限 (LOD) 和定量限 (LOQ) 分别为 0.2–0.5 和 0.5–1.5 µg L ^–1。添加不同浓度三嗪的真实水样的相对回收率 (RR) 为 91-107.8%。