Elastic Polymer Coated Nanoparticles with Fast Clearance for 19F MR Imaging,Angewandte Chemie International Edition

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Elastic Polymer Coated Nanoparticles with Fast Clearance for 19F MR Imaging
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2023-08-17 , DOI: 10.1002/anie.202308565
Yuki Konishi ₁ , Masafumi Minoshima _{1,

2} , Kohei Fujihara ₃ , Takayuki Uchihashi _{3,

4} , Kazuya Kikuchi _{1,

5}

Affiliation

Elastic polymer-coated nanoparticles (NPs) were developed as novel contrast agents for ¹⁹F MRI. These NPs encapsulated liquid perfluorocarbon, resulting in high elasticity and robust sensitivity in ¹⁹F NMR and MRI. Moreover, in vivo imaging of these NPs implied that elastic NPs suppressed long-term accumulation in the liver.

中文翻译：

用于 19F MR 成像的具有快速清除能力的弹性聚合物涂层纳米颗粒

弹性聚合物涂层纳米粒子 (NP) 被开发为¹⁹ F MRI 的新型造影剂。这些纳米粒子封装了液体全氟化碳，从而在¹⁹ F NMR 和 MRI 中具有高弹性和强大的灵敏度。此外，这些纳米粒子的体内成像表明，弹性纳米粒子抑制了肝脏中的长期积累。

更新日期：2023-08-17

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