1 ​wt% Ru/5 ​wt% Nb₂O₅/CeO₂ (RuNbCe) catalyst was synthesized via the incipient wetness impregnation method, and measured for the catalytic oxidation of dichloromethane (DCM). The physicochemical properties of catalysts were determined used various characterization techniques. Compared with 1 ​wt% Ru/CeO₂, 5 ​wt% Nb₂O₅/CeO₂, CeO₂, 1 ​wt% Ru/xNb₂O₅/CeO₂ (x ​= ​1 ​wt%, 2 ​wt%, and 3 ​wt%) and 1 ​wt% Ru/yMO_n/CeO₂ (M ​= ​Co, Cr, Fe, Mg, Cu; y ​= ​5 ​wt%), the addition of 5 ​wt% Nb₂O₅ obviously improved the catalytic performance of 1 ​wt% Ru/CeO₂, with the T_90% and apparent activation energy (E_a) being 287 ^oC and 43.5 ​kJ/mol, respectively, and less formation of polychlorinated byproducts at space velocity (SV) ​= ​15,000 ​mL ​g^‒1 ​h^‒1. The RuNbCe catalyst showed good thermal and hydrothermal stability, as well as HCl-resistance performance. We deduced that the higher oxidation performance of the RuNbCe catalyst may be attributed to the suitable acidic sites, good redox capacity, high surface adsorbed oxygen species concentration, and the strong interaction among Ru, Nb₂O₅ and CeO₂. The RuNbCe catalyst has the potential to be applied for the elimination of chlorinated volatile organic compounds (CVOCs).