Catalpol is a kind of iridoid glucoside, widely found in a variety of plants, mostly extracted from the rhizome of the traditional medicinal herb rehmanniae. It has various biological activities such as anti-inflammatory, antioxidant, and antitumor. The anti-inflammatory effects of catalpol have been demonstrated in a variety of diseases, such as neurological diseases, atherosclerosis, renal diseases, respiratory diseases, digestive diseases, bone and joint diseases, eye diseases, and periodontitis. The purpose of this review is to summarize the existing literature on the anti-inflammatory effects of catalpol in a variety of inflammatory diseases over the last decade and to focus on the anti-inflammatory mechanisms of catalpol.

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梓醇对多种炎症性疾病的抗炎作用及机制

梓醇是环烯醚萜苷的一种，广泛存在于多种植物中，多从传统药材地黄的根茎中提取。具有抗炎、抗氧化、抗肿瘤等多种生物活性。梓醇的抗炎作用已在多种疾病中得到证实，如神经系统疾病、动脉粥样硬化、肾脏疾病、呼吸系统疾病、消化系统疾病、骨关节疾病、眼部疾病、牙周炎等。本文综述近十年来有关梓醇在多种炎症性疾病中抗炎作用的现有文献，重点探讨梓醇的抗炎机制。