The green technique for the preparation of different nanoparticles is an eco-friendly, economically, and safe technology. In this research, Gold nanoparticles (SS-AuNPs) were prepared by the rapid, inexpensive and eco-friendly process using Scrophularia striata extract as a reducing, capping, and stabilizing agent for the first time. The formation of nanoparticles was confirmed using various analytical methods, including UV/Vis, XRD, EDX, TEM, FT-IR, FE-SEM techniques. UV–Vis data indicated the “surface plasmon resonance” band at 575 nm. The electron microscopy data exhibited that synthesized AuNPs had mostly spherical in shape with a mean crystaline size of 34.6 nm. The spherical crystalline nature of the synthesized NPs was demonstrated by the XRD analysis and the average size was determined at 21.35 nm. Prepared SS-AuNPs exhibited good antibacterial activity against tested bacteria. The MIC values of 11.875, 95, 47.5, 47.5, 23.75, 11.875, and 47.5 µg/ml on strains Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, Klebsiella pneumonia, and Proteus mirabilis were determined respectivly. Also, SS-AuNPs showed effective antileishmanial activity, the anti-promastigotes activity of SS-AuNPs was calculated as IC₅₀ values of 0.12 µg/ml and the anti-amastigote activity of SS-AuNPs was determined as IC₅₀ values of 0.07 µg/ml. Potentially inhibited DPPH ( 2,2-diphenyl-1-picrylhydrazyl) radicals (IC₅₀ = 15.81 µg/ml). Synthesized gold nanoparticles as a noble nanocatalyst act for the reduction of methyl orange (MO) that was in the presence of visible light and sodium borohydride. Where 50 μl of prepared AuNPs, completely degraded MO dye in 5 min. The results of this study indicate that gold nanoparticles, which were mediated by S. stratia extract, possess great potential for application in a wide range of fields, such as industrial wastewater treatment and biomedical sectors.

制备不同纳米粒子的绿色技术是一种环境友好、经济、安全的技术。在这项研究中，利用玄参通过快速、廉价且环保的工艺制备了金纳米颗粒（SS-AuNP）首次将提取物作为还原剂、封端剂和稳定剂。使用各种分析方法证实了纳米颗粒的形成，包括 UV/Vis、XRD、EDX、TEM、FT-IR、FE-SEM 技术。紫外-可见光数据表明“表面等离子共振”带位于 575 nm。电子显微镜数据显示，合成的AuNPs大多呈球形，平均晶体尺寸为34.6 nm。XRD 分析证明了合成纳米颗粒的球形结晶性质，平均尺寸为 21.35 nm。制备的 SS-AuNPs 对测试细菌表现出良好的抗菌活性。对金黄色葡萄球菌、粪肠球菌、铜绿假单胞菌、不动杆菌菌株的 MIC 值为 11.875、95、47.5、47.5、23.75、11.875 和 47.5 µg / ml分别测定鲍曼不动杆菌、大肠杆菌、肺炎克雷伯菌、奇异变形杆菌。此外，SS-AuNPs 显示出有效的抗利什曼原虫活性，SS-AuNPs 的抗前鞭毛体活性计算为 IC ₅₀值为 0.12 µg/ml，SS-AuNPs 的抗鞭毛体活性计算为 IC ₅₀值为 0.07 µg/ml。毫升。潜在抑制 DPPH（ 2,2-二苯基-1-三硝基苯肼）自由基 (IC ₅₀ = 15.81 微克/毫升）。合成的金纳米颗粒作为一种高贵的纳米催化剂，在可见光和硼氢化钠存在下可还原甲基橙 (MO)。其中50μl制备的AuNPs，在5分钟内完全降解MO染料。这项研究的结果表明，以S. stratia提取物介导的金纳米颗粒在工业废水处理和生物医学领域等广泛领域具有巨大的应用潜力。