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Isolation of Two Plasticizers, Bis(2-ethylhexyl) Terephthalate and Bis(2-ethylhexyl) Phthalate, from Capparis spinosa L. Leaves
Chemistry & Biodiversity ( IF 2.3 ) Pub Date : 2023-07-28 , DOI: 10.1002/cbdv.202300903
Ayoub Kdimy 1, 2 , Seong Jong Kim 3 , Zulfiqar Ali 4 , Md Imdadul H Khan 1 , Siddharth K Tripathi 4 , Souad El Hajjaji 2 , Hoang V Le 1, 5
Affiliation  

Many plants have been known to be contaminated and accumulate plasticizers from the environment, including water sources, soil, and atmosphere. Plasticizers are used to confer elasticity and flexibility to various fiber and plastic products. Consumption of plasticizers can lead to many adverse effects on human health, including reproductive and developmental toxicity, endocrine disruption, and cancer. Herein, we report for the first time that two plasticizers, bis(2-ethylhexyl) terephthalate (DEHT) and bis(2-ethylhexyl) phthalate (DEHP), have been isolated from the leaves of Capparis spinosa L. (the caper bush), a plant that is widely used in food seasonings and traditional medicine. 297 mg/kg of DEHT and 48 mg/kg of DEHP were isolated from dried and grounded C. spinosa L. leaves using column chromatography and semi-preparative high-performance liquid chromatography. Our study adds to the increase in the detection of plasticizers in our food and medicinal plants and to the alarming concern about their potential adverse effects on human health.

中文翻译:

从刺山柑叶中分离两种增塑剂:对苯二甲酸双(2-乙基己基)酯和邻苯二甲酸双(2-乙基己基)酯

已知许多植物受到污染,并从环境(包括水源、土壤和大气)中积累增塑剂。增塑剂用于赋予各种纤维和塑料产品弹性和柔韧性。食用增塑剂会对人类健康产生许多不利影响,包括生殖和发育毒性、内分泌干扰和癌症。在此,我们首次报道从 Capparis spinosa L.(刺山柑灌木)的叶子中分离出两种增塑剂:对苯二甲酸双(2-乙基己基)酯 (DEHT) 和邻苯二甲酸双(2-乙基己基)酯 ( DEHP ) ,一种广泛用于食品调味料和传统药物的植物。使用柱色谱法和半制备型高效液相色谱法从干燥并磨碎的刺角C. spinosa L. 叶子中分离出 297 mg/kg DEHT 和 48 mg/kg DEHP 。我们的研究增加了食品和药用植物中增塑剂检测的增加,并增加了人们对其对人类健康潜在不利影响的担忧。
更新日期:2023-07-28
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